Preschoolers not offered sufficient physical activity time
1. Preschool children did not have opportunities to engage in active play time for the majority (88%) of their time spent at childcare facilities. 2. Children were more physically active when given...
View ArticleApplicants given extra time on MCAT have lower USMLE pass rates
1. Individuals with extra time testing accommodations on the Medical College Admissions Test (MCAT) had comparable scores and medical school admissions outcomes to those taking the MCAT in the standard...
View ArticleMindfulness-based therapy associated with improvement in quality of life for...
1. In this study, mindfulness-based stress reduction (MBSR) therapy resulted in a greater reduction in self-reported post-traumatic stress disorder (PTSD) symptoms and improved quality of life compared...
View ArticleVariation noted across pre- and post-marketing studies for FDA approved devices
1. This study found that in addition to the pivotal study required for approval, the Food and Drug Administration (FDA) approved high-risk medical devices had a median number of 1 nonpivotal study...
View ArticleDietary doses of resveratrol may inhibit development of colorectal cancer...
1. On a high-fat diet (HFD), mice genetically predisposed to colorectal cancer (ApcMin mice) developed fewer and smaller tumors when maintained on a diet-relevant low dose of resveratrol as compared to...
View ArticleUse of elotuzumab with conventional therapy linked to improved survival in...
1. Adding elotuzumab to the conventional lenalidomide and dezamethasone was associated with a 30% reduction in the risk of disease progression or death in relapsed or refractory multiple myeloma (MM)...
View ArticleLong-term use of NSAIDs and aspirin linked to lower risk of colorectal cancer
1. From a case-control study, using nonsteroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin continuously for over 5 years was associated with lower risk of colorectal cancer. 2. Rectal...
View ArticleImetelstat associated with rapid hematological responses in essential...
1. Imetelstat induced hematologic responses in 100% of essential thrombocythemia (ET) patients and prolonged treatment was associated with more gradual increases after the discontinuation of treatment....
View ArticleGender differences in academic achievement exist in medicine
1. This study found that women were less likely than men to be full professors, have first and last author publications, and have funding from the National Institutes of Health. 2....
View ArticleApgar score not predictive of mortality or neurological outcome
1. The Apgar score evaluates initial infant condition after delivery and helps direct need for any resuscitative measures. This joint policy from the American Academy of Pediatric (AAP) and the...
View ArticleOlaparib linked to increased response in metastatic, castration-resistant...
1. In this phase II trial, use of the poly(adenosine diphosphate[ADP]-ribose) polymerase (PARP) inhibitor olaparib showed a positive response in a subset of metastatic castration-resistant prostate...
View ArticleOutcomes remain poor in locally advanced pancreatic cancer
1. Compared to induction chemotherapy alone, maintenance chemoradiotherapy did not prolong overall survival or time to disease progression in patients with locally advanced pancreatic cancer. 2....
View ArticleBMI linked with lowest mortality has increased over past few decades
1. The body mass index (BMI) associated with the lowest level of all-cause mortality increased by 3.3 over the past 3 decades in a cohort from Copenhagen. 2. There was a U-shaped relationship between...
View ArticleRespiratory symptoms frequent in smokers despite normal spirometry: The...
1. Symptomatic smokers with preserved spirometric measurements had a significantly higher rate of respiratory exacerbations than both asymptomatic smokers with preserved spirometric measures and...
View ArticleAssociation of a genetic risk score with body mass index across several birth...
1. This observational study found that BMI is associated with a genetic risk score calculated from multiple loci. 2. This association is present in both white and black cohorts, with the magnitude of...
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